Endocrine Abstracts

To determine a correlation between Vitamin D, GH, IGF1 and cardiovascular risk we enrolled. 41 GHD patients (22 M, 19 F, age 18–84 years) and 41 controls. In all we determined: anthropometric parameters, blood pressure (BP), lipid and glucose profile, PTH, 25-OH-vitamin D, GH peak after GHRH+ARG, IGF1. Metabolic syndrome (MS) was evaluated by the IDF criteria.The vitamin D were lower in patients than in controls (21.3±12.3 vs 28.2±9.4, <em...

Context: Until now the role of medical therapy in patients with primary hyperparathyroidism (PHP) was mainly based on the use of bisphosphonates. Recently, cinacalcet hydrochloride was reported to be effective in control hypercalcemia in PHP. The aim of this study was to evaluate the efficacy of cinacalcet in PHP patients who were not effectively controlled with alendronate.Patients and methods: Fourteen PHP patients (mean age 64.1±2.6) were include...

Introduction and Aim: Polycystic Ovary Syndrome (PCOS) is an endocrine disease closely related to several risk factors for cardiovascular disease. Previous study demonstrated an impaired cardiopulmonary functional capacity in PCOS women. The present study was performed to evaluate the effects of 3-months exercise training (ET) programme on cardiopulmonary functional capacity in young women with PCOS.Patients and Methods: The study was conducted according...

Introduction and aim: Polycystic Ovary Syndrome (PCOS) is a common disorder associated with a wide range of endocrine and metabolic abnormalities. Obesity is present in about 45–50% of PCOS women. Increased cardiovascular risk factors and evidence of subclinical cardiovascular disease (CVD) have been reported in PCOS. The aim of the present study was to evaluate whether visceral fat amount may be considered as predictor for early CVD in PCOS women.P...

The GH/IGF-I axis function are reported to ameliorate after weight-loss. Bariatric surgery leads to a significant weight loss in morbidly obese patients. We investigated the relationships between GH/IGF-I axis and body composition in 20 morbidly obese females (BMI: 44.8±4.7; waist circumference (W) 119.5±7.2 cm, age 33.7±11.7 yrs) with a normal glucose tolerance, before and after laparoscopic silicone adjustable-gastric banding (LASGB). The GH axis was evaluated...